Understanding Diabetes Types and Causes, Chapter 3: Insulin Resistance

How the Pancreas Responds to Resistance

The pancreas may make extra insulin when cells respond less well, and that can change over years.

Explain why the pancreas may make more insulin when cells resist its signal.

Insulin is like a key. It opens the doors of your cells. When the doors open, cells can take in sugar from your blood.

Sometimes the cell doors open less easily. This is called insulin resistance. The same key still works, but it takes more effort.

Your pancreas makes insulin. When cells respond less well, it may release more insulin to make up for it.

For a time, extra insulin can keep blood sugar near normal. Your readings may look fine while cells respond less well.

It is like a duck on a pond. The surface looks calm while the feet paddle hard underneath.

That is why insulin resistance can go unnoticed. A normal reading does not always mean the cells respond well.

Cells that respond less well need more insulin to do their job. That need is called demand. The pancreas works to meet demand, but over years it may struggle to keep up.

When it falls behind, blood sugar tends to rise bit by bit. That slow rise is one reason type 2 diabetes builds slowly.

Key takeaways

  • The pancreas may release more insulin when cells respond less well.
  • Extra insulin can keep blood sugar near normal for a time.
  • Over years, the pancreas may struggle, so blood sugar tends to rise gradually.

Try it

At your next visit, ask your care team which of your results they follow over time. Write down their answer.

Next lesson: Weight and Insulin Sensitivity